pentobarbital will decrease the extent or influence of diazepam by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Keep track of.
pentobarbital will minimize the level or influence of oxybutynin by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Insignificant/Importance Unfamiliar.
pentobarbital decreases outcomes of sufentanil SL by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Modify Therapy/Monitor Closely. Coadministration of CYP3A4 inducers may possibly minimize sufentanil amounts and efficacy, quite possibly precipitating withdrawal syndrome in patients that have formulated Bodily dependence to sufentanil. Discontinuation of concomitantly utilised CYP3A4 inducers may perhaps improve sufentanil plasma concentration.
Keep an eye on Carefully (1)pentobarbital will reduce the level or impact of exemestane by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Check. For individuals acquiring exemestane with a strong CYP3A4 inducer the advisable dose of exemestane is 50 mg everyday following a meal.
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benzhydrocodone/acetaminophen and pentobarbital both equally raise sedation. Stay clear of or Use Alternate Drug. Restrict use to patients for whom alternative treatment options are insufficient
pentobarbital will lessen the level or outcome of nicardipine by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Watch.
Observe Carefully (one)pentobarbital will decrease the level or effect of tofacitinib by read more impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Watch. Loss of, or reduced response to tofacitinib may possibly take place when coadministered with powerful CYP3A4 inducers
pentobarbital will reduce the level or result of etoposide by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Watch.
pentobarbital will lessen the extent or impact of ramelteon by influencing hepatic enzyme CYP2C9/ten metabolism. Small/Importance Mysterious.
Observe Carefully (one)pentobarbital will lower the extent or effect of osilodrostat by affecting hepatic/intestinal enzyme CYP3A4 metabolism.
pentobarbital will minimize the level or influence of bosentan by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Slight/Significance Unfamiliar.
pentobarbital will reduce the level or outcome of ketoconazole by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Slight/Importance Not known.
Keep an eye on Carefully (one)pentobarbital will lessen the extent or influence of benzhydrocodone/acetaminophen by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Modify Therapy/Keep an eye on Closely. Warning when discontinuing CYP3A4 inducers which have been coadministered with benzhydrocodone (prodrug of hydrocodone); plasma concentrations of hydrocodone might boost and may lead to probably lethal respiratory melancholy.